[BioNEC-48] Stella, Stefano; Mesa, Pablo; Thomsen, Johannes; Paul, Bijoya; Alcon, Pablo; Jensen, Simon B.; Saligram, Bhargav; Moses, Matias E.; Hatzakis, Nikos S.; Montoya, Guillermo. Conformational activation promotes CRISPRCas12a catalysis and resetting of the endonuclease activity. Cell (2018) 175, 1856–1871. [Abstract]
[BioNEC-47] Ferino, Annalisa; Miglietta, Giulia; Picco, Raffaella; Vogel, Stefan; Wengel, Jesper; Xodo, Luigi E. MicroRNA therapeutics: Design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells. RNA Biology (2018), 15, 1273-1285. [Abstract]
[BioNEC-46] Martos-Maldonado, Manuel C.; Hjuler, Christian T.; Sørensen, Kasper K.; Thygesen, Mikkel B.; Rasmussen, Jakob E.; Villadsen, Klaus; Midtgaard, Søren R.; Kol, Stefan; Schoffelen, Sanne; Jensen, Knud J. Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence. Nature Commun. (2018), 9, 3307. [Abstract]
[BioNEC-45] Ejlersen, Maria; Lou, Chenguang; Sanghvi, Yogesh S.; Tor, Yitzhak; Wengel, Jesper. Modification of oligodeoxynucleotides by on-column Suzuki cross-coupling reactions. Chem. Commun. (2018), 54, 8003–8006. [Abstract]
[BioNEC-44] Østergaard, Mads; Christensen, Niels Johan; Hjuler, Christian T.; Jensen, Knud J.; Thygesen, Mikkel B. Glycoconjugate oxime formation catalyzed at neutral pH: Mechanistic insights and applications of 1,4-diaminobenzene as a superior catalyst for complex carbohydrates. Bioconjug. Chem. (2018), 29, 1219-1230. [Abstract]
[BioNEC-43] Ejlersen, Maria; Christensen, Niels Johan; Sørensen, Kasper K.; Jensen, Knud J.; Wengel, Jesper; Lou, Chenguang. Synergy of two highly specific biomolecular recognition events: Aligning an AT-hook peptide in DNA minor grooves via covalent conjugation to 2'-amino-LNA. Bioconjug. Chem. (2018), 29, 1025-1029. [Abstract]
[BioNEC-42] Vejlegaard, Kim; Wegeberg, Christina; McKee Vickie; Wengel, Jesper. Novel conformationally constrained 2′-C-methylribonucleosides: Synthesis and incorporation into oligonucleotides. Org. Biomol. Chem. (2018),16, 1312-1321 [Abstract]
