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Clinical Genome Center

Research Projects

Clinical Genome Center activity

The center gives support to the following PhD projects:

 

Alexander Venzel Rudbeck

Main supervisor: Mads Thomassen, professor.

Dept. of Clinical Genetics, OUH and the Dept. of Clinical Research, SDU.

 

Christine Fribert Thusgaard

Main supervisor: Kirsten M. Jochumsen, MD.

Dept. of Gynaecology and Obstetrics - D, OUH and the Dept. of Clinical Research, SDU.

Title: “Genova: Improving Survival of Ovarian Cancer by Early Detection of Recurrence Using Circulating Tumor DNA”.

 

Emilie Boye Lester

Main supervisor: Martin J. Larsen, associate professor.

Dept. of Clinical Genetics, OUH and the Dept. of Clinical Research, SDU.

Title: “Long-Read Whole Genome Sequencing - 3rd Generation Nanopore Sequencing In Clinical Genetic Diagnostic”.

 

Laura Catalini

Main supervisor: Jens Fedder, professor, MD.

Dept. of Clinical Research, SDU and Dept. of Gynaecology and Obstetrics - D, OUH.

Title: "Modification of Endometrial Receptivity after Vaginal Plasma Application: Randomized Controlled Trial".

 

Louise Adel Jensen

Main supervisor: Mads Thomassen, professor.

Dept. of Clinical Genetics, OUH and the Dept. of Clinical Research, SDU.

Title: "The Molecular Characterization of Familial Breast Cancer with no Confident Genetic Explanation - Identification of Subgroups and Classification of Genetic Variants".

 

Louise Geertsen

Main supervisor:  Lars Lund, professor, MD.

Department of Urology L, OUH and the Dept. of Clinical Research, SDU.

Title: "KIDSTAGE; Staging of Kidney Cancer Using Dual Time PET/CT and Other Biomarkers".

 

Mikkel Møller Henriksen

Main supervisor: Mads Thomassen, professor.

Dept. of Clinical Genetics, OUH and the Dept. of Clinical Research, SDU.

Title: "Characterization of Tumor Load and Mutational Profile in Patients with Gastroesophageal Cancer Using Circulating Tumor DNA".

Nhu Do

Main supervisor: Torben A. Kruse, professor.

Dept. of Clinical Genetics, OUH and the Dept. of Clinical Research, SDU.

Title: "Integrated Genomic Analysis of Breast Tumors. A Possible Tool towards Reduction of Overtreatment".

 

Zainab Hikmat

Main supervisor: Vibeke Andersen, clinical professor, MD.

Molecular and Diagnostic Research Unit, Hospital of Southern Jutland and Institute of Molecular Medicine, and Institute of Regional Health Research, SDU.

Title: "Predicting Response to Medical Treatment of Inflammatory Bowel Diseases (IBD) Using Single  Cell Transcriptomic on Intestinal Biopsies: a Prospective Cohort Study of Personalized Medicine".

 

 

 

Some of the completed PhD projects performed either at or in collaboration with CGC:

 

Stephanie Kavan

Main supervisor: Mads Thomassen, professor.

Dept. of Clinical Genetics, OUH and the Dept. of Clinical Research, SDU.

Title: "Genomic Analysis of Metastatic Breast Cancer – Exome sequencing of Primary Tumor, Circulating Tumor DNA and Metastasis”.

 

Ming Tan

Main supervisor: Maiken T. Jørgensen, clinical associate professor, MD.

Dept. of Clinical Research, SDU and Dept. of Medical Gastrointestinal Diseases  –  S, OUH.

Title: “Genetic Markers Predictive of Familial Pancreatic Cancer”.

 

Ieva Miceikaite

Main supervisor: Martin J. Larsen, associate professor.

Dept. of Clinical Genetics, OUH and the Dept. of Clinical Research, SDU.

Title: “Non-Invasive Prenatal Diagnostics Using Deep Exome Sequencing (DES-NIPT)”.

 

Jeanne Mari Vejen Bang

Main supervisor: Brage S. Andresen, professor.

Dept. of Biochemistry and Molecular Biology, SDU.

Title: "RBM10, a Regulatory Center – How Do Changes in the RBM10 Gene Lead to a New Syndrome with Intellectual Disability and to TARP Syndrome?".

 

Christina Mortensen

Main supervisor: Tore Bjerregaard Stage, associate professor.Dept. of Clinical Pharmacology, Pharmacy and Environmental Medicine, SDU

Title: “Molecular Mechanisms and Drug Transport in Chemotherapy-Induced Peripheral Neuropathy".

 

Kirstine Øster Andersen

Main supervisor: Henrik B.T. Christesen, associate professor, MD.

H. C. Andersen Children's Hospital - H, OUH, and the Dept. of Clinical Research, SDU.

Title: "Genetic Alterations in Insulinomas with and without Multiple Endocrine Neoplasia Type 1; Understanding Tumourigenesis in Beta-Cells".

 

Stine Bjørn Gram

Main supervisor: Lilian B. Ousager, professor, MD, head of department.

Dept. of Clinical Genetics, OUH and the Dept. of Clinical Research, SDU.

Title: ”Improved Genetic Diagnostics and Characteristics of Inherited Palmoplantar Keratoderma”.

 
Mirolyuba Ilieva

Main supervisor: Tanja M. Sheldrick-Michel, professor, MD.

Psychiatric hospital, Odense and the Dept. of Clinical Research, SDU.

 

Nanna Elman Andersen:

Main supervisor: Tore Bjerregaard Stage, associate professor.

Dept. of Clinical Pharmacology, Pharmacy and Environmental Medicine, SDU.

Title: "Mechanisms of chemotherapy neurotoxicity and transport in iPSC-derived Schwann cells".

 

 

 

Last Updated 28.05.2024