Publications from the Lab
Link to Publications by Nils Færgeman on PubMed
Most recent Publications from the Lab
Acute deletion of the glucocorticoid receptor in hepatocytes disrupts postprandial lipid metabolism in male mice
Correia et al., Endocrinology, 2023, Aug. 23
Distinct maternal metabolites are associated with obesity and glucose-insulin axis in the first trimester of pregnancy
Bandres-Meriz et al., Int J Obes (Lond), 2023, Jul.
NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner
Basse et al., Proc Natl Acad Sci USA, 2023, Apr. 4
An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention
Jørsboe et al., HGG Adv 2022, Jun. 9
High-fat diet-induced obesity augments the deleterious effects of estrogen deficiency on bone: Evidence from ovariectomized mice
Ali et al., Aging Cell 2022, Dec. 21
GIP Affects Hepatic Fat and Brown Adipose tissue Thermogenesis but Not White Adipose Tissue Transcriptome in Type 1 Diabetes
Heimbürger et al., J Clin Endochrinol Metabolism 2022, Nov. 25
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis
Loft et al., Cell Metabolism 2022, Mar. 1
Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism
Okarmus et al., Stem Cell Reports 2021, Jun. 8
Loss of sucrase-isomalatase function increases acetate levels and improves metabolic health in Greenlandic cohorts
Andersen et al., Gastroenterology 2021, Dec. 13
Impaired glucocorticoid receptor expression in liver disrupts feeding-induced gene expression, glucose uptake, and glycogen storage
Præstholm et al., Cell Reports 2021, Nov 2
From benzodiazepines to fatty acids and beyond: revisiting the role of ACBP/DBI
Alquier et al., Trends Endocrinol Metab 2021, Nov
Characterising Alzheimer’s disease through integrative NMR- and LC-MS-based metabolomics
Nielsen et al., Metabolism Open 2021, Sep 22
Patched regulates lipid homeostasis by controlling cellular cholesterol levels
Cadena Del Castillo et al., Nat Commun. 2021, Aug 12
Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism
Okarmus et al., Stem Cell Reports 2021 May 27
HLH-30-dependent rewiring of metabolism during starvation in C. elegans
Dall et al., Aging cell 2021, Mar 16
Lipid molecular timeline profiling reveals diurnal crosstalk between the liver and circulation
Sprenger et al., Cell Reports 2021 Feb , 34
Epidermal Acyl-CoA-binding protein is indispensable for systemic energy homeostasis
Neess et al., Molecular Metabolism 2021 Feb , 44
Type III-A CRISPR-associated protein Csm6 degrades cyclic hexa-adenylate activator using both CARF and HEPN domains
Smalakyte et al., Nucleic Acids Res 2020 7
Ethyl Pyruvate Increases Post-Ischemic Levels of Mitochondrial Energy Metabolites: A 13C-Labeled Cerebral Microdialysis Study
Nygaard et al., Metabolites 2020 July 13, 10(7), 287
Free Fatty Acids Interfere with the DNA Binding Activity of the Virulence Regulator PrfA of Listeria monocytogenes
Dos Santos et al., J Bacteriol 2020 July 9
The Yeast Sphingolipid Phospholipase ISC1 Regulates The Spindle Checkpoint In a CDC55-Dependent Mechanism
Matmati et al., Mol Cell Biol 2020 March
Expression of acyl-CoA-binding protein 5 from Rhodnius prolixus and its inhibition by RNA interference
Almeida et al., PLOS One 2020 Jan
Metabolic programming determines the lineage-differentiationfate of murine bone marrow stromal progenitor cells
Tencerova et al., Bone Research 2019 Nov, 7, 35
In Vivo Microdialysis of Endogenous and 13C-labeled TCA Metabolites in Rat Brain: Reversible and Persistent Effects of Mitochondrial Inhibition and Transient Cerebral Ischemia
Havelund et al., Metabolites 2019 Oct, 9(10), 204
Metabolic regulation of lifespan from a C. elegans perspective
Dall and Færgeman, Genes and Nutrition 2019 Aug, 14, 25
Autophagy-Mediated Cholesterol Trafficking Controls Steroid Production
Taxada et al., Developmental Cell 2019 Mar 11, 48, 659-671
Axon-Dependent Patterning and Maintenance of Somatosensory Dendritic Arbors
Ramirez-Suarez et al., Developmental Cell 2019 Jan 28, 48(2), 229-244
LC-MS Analyses of Lipid Species in Skeletal Muscle Cells and Tissue
Morreno-Torres et al., Methods Mol Biol. 2018, 1889, 213-228
A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
Hansen et al., Nat Commun. 2018 Nov 13, 9(1), 4630
Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle
Hingst et al., Mol Metab. 2018 Oct 16, 24-34
Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
Sustarsic et al., Cell Metab. 2018 Jul 3, 28(1), 159-174
Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine
Christensen et al., BMJ Open. 2018 Feb 8, 8(2)
Carnitine acetyltransferase: A new player in skeletal muscle insulin resistance?
Berg et al., Biochem Biophys Rep. 2016 Nov 18, 9, 47-50
Elimination of the last reactions in ergosterol biosynthesis alters the resistance of Saccharomyces cerevisiae to multiple stresses
Liu et al., FEMS Yeast Res. 2017 Sep 1, 17(6)
Biomarker Research in Parkinson's Disease Using Metabolite Profiling
Havelund et al., Metabolites. 2017 Aug 11, 7(3)
HIF-1-dependent regulation of lifespan in Caenorhabditis elegans by the acyl-CoA-binding protein MAA-1
Shamalnasab et al., Aging (Albany NY). 2017 Jul 27, 9(7), 1745-1769
Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans
Harvald et al., Cell Syst. 2017 Jul 26, 5(1), 38-52
The Significance of Epidermal Lipid Metabolism in Whole-Body Physiology
Kruse et al., Trends Endocrinol Metab. 2017 Sep 28, 9, 669-683
Changes in kynurenine pathway metabolism in Parkinson patients with L-DOPA-induced dyskinesia
Havelund et al., J Neurochem. 2017 Sep, 142(5), 756-766
Sphingolipids: membrane microdomains in brain development, function and neurological diseases
Olsen ASB and Færgeman NJ, Open Biol. 2017 May 7, 5
A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine
Andersen et al., Nutrients. 2017 May 15, 9(5)
The heterozygous N291S mutation in the lipoprotein lipase gene impairs whole-body insulin sensitivity and affects a distinct set of plasma metabolites in humans
Berg et al., J Clin Lipidol. 2017 Mar – Apr 11(2), 515-523
Antimicrobial medium- and long-chain free fatty acids prevent PrfA-dependent activation of virulence genes in Listeria monocytogenes
Sternkopf Lillebæk et al., Res Microbiol. 2017 Jul – Aug, 168(6), 547-557
Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein
Ferreira et al., J Biol Chem. 2017 May 5, 292(18), 7588-759
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy
Zimmermann et al., Cell Rep. 2017 Feb 21, 18(8), 2073-2074
Quantitative lipidomics reveals age-dependent perturbations of whole-body lipid metabolism in ACBP deficient mice
Gallego et al., Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Feb, 1862(2), 145-155
Ribonuclease-Mediated Control of Body Fat
Habacher et al., Developmental Cell 2016 Nov 7, 39(3), 359-369 From benzodiazepines to fatty acids and beyond: revisiting the role of ACBP/DBI