Ole Nørregaard Jensen is professor and group leader in the Protein Research Group. My research is focused on understanding chromatin dynamics and the role of proteins in disease development. I am developing and using advanced mass spectrometry technologies and computational methods (bioinformatics, machine learning) to obtain information on protein structure and function in biological samples and clinical specimen. I am currently focusing on cancer research (kidney cancer), detailed structure elucidation of intact proteins, and the development of ultra-sensitive bioanalytical methods for detection of proteins in small sample volumes, down to the single cell level. Integration of experimental methods with advanced computational algorithms and machine learning is key to achieve my research goals.
List of recent publications (PubMed).
Research projects:
-Classification of kidney cancer tumors using mass spectrometry imaging and proteomics.
-Unraveling the role of histone proteins in chromatin biology and disease (cancer).
-Structure analysis of biologicals (protein drugs), such as EPO and antibodies.
-Chromatography and mass spectrometry technology, including ion mobility spectrometry and tandem mass spectrometry, for protein characterization.
-Computational and statistics tools for large-scale data analysis.
Director, VILLUM Center for Bioanalytical Sciences
Director, PRO-MS, Danish National Mass Spectrometry Platform for Functional Proteomics
Head of research: Professor, PhD Ole Nørregaard Jensen
Researchers and research group: Ole Nørregaard Jensen Lab
Group webpage: Protein
A complete list of publications by Ole Nørregaard Jensen can be found here.
Part of the Research section of Biomedical Mass Spectrometry at the Department of Biochemistry and Molecular Biology
